Our team of biophysicists, biochemists, mathematicians and physicians explores platelets - the smallest, but very mysterious cells of our body. We are studying the fundamental features of their life and death - intracellular signaling, metabolism, programmed cell death, mechanisms of adhesion, participation in blood coagulation and immunity, role in thrombosis and hemostasis - and then use this knowledge for practical purposes: to develop new and to explore the existing drugs, creation and improvement of methods of diagnosis, identifying the nature of blood disorders. The peculiarity of our approach is the use of modern methods of biophysics and systems biology, especially the combination of computer and mathematical modeling with experiments. Our main experimental base is Federal Research Center of Pediatric Hematology, Oncology and Immunology. And the center of theoretical studies is Faculty of Physics, Lomonosov Moscow State University. Team leader - Prof. Mikhail Panteleev, head of Laboratory of cellular hemostasis of FRC PHOI and prof. of the Department of Medical Physics of the Faculty of Physics, MSU.